This webinar discusses the procedure to be used in the dissolution testing of gelatin capsules when they fail the two-tier dissolution test. The webinar will include discussion of crosslinking in gelatin, its causes and prevention; quality requirements of the enzymes to be used and the procedure to determine their activity; and alternative procedures when the dissolution medium contains surfactants. A report on the activities related to the revision of this procedure in USP General Chapter <711> Dissolution will be presented.
Couse Duration (hh:mm:ss): 01:30:00
Margareth Marques Ph.D.
Principal Scientific Liaison – USP
Ph.D., Analytical Chemistry, Universidade Estadual de Campinas